What is triple negative breast cancer?

1. Definition

Triple-negative breast cancer (TNBC) refers to the type of breast cancer that lacks estrogen receptors (ER), progesterone receptors (PR) and HER2 receptors, accounting for approximately all 15% of breast cancer.

2. Features

– High incidence rate: It is more common in women under the age of 40, which is different from the general breast cancer that mostly occurs between the ages of 45-69.

– Rapid growth: TNBC cancer cells proliferate quickly, and tumors grow and metastasize rapidly in a short period of time.

– High metastasis rate: easily metastasizes to the brain, lungs and lymph nodes, resulting in higher mortality.

3. Dangerous Groups

– BRCA gene variants: BRCA1 gene variants are closely associated with TNBC.

– Family history: Women who have a family history of breast cancer or have had unilateral breast cancer.

4. Symptoms

– Common symptoms:

– Breast lump

– Nipple erosion

– Breast sunken

– Swollen lymph nodes under armpit

– Metastasis symptoms: When cancer spreads to the lungs, liver or brain, patients may experience chest tightness, chest pain, difficulty breathing, dizziness and other symptoms.

5. Treatment

TNBC mainly relies on chemotherapy treatment. Due to the lack of hormonal therapy and targeted therapy options, the prognosis is usually poor.

Why is triple-negative breast cancer so dangerous?

1. High recurrence rate

TNBC cancer cells are highly genetically mutated and have a higher risk of recurrence.

2. High transfer rate

Cancer cells can easily metastasize to the brain, lungs and lymph nodes, causing more serious health problems.

3. Lack of effective treatment options

Hormone and targeted therapies are not available due to lack of ER, PR and HER2 receptors.

4. High malignancy

Cancer cells grow rapidly, and tumors expand and metastasize quickly.

5. Most of the patients are young

TNBC is more common in women under the age of 40, and patients face longer-term health risks.

6. Genetic factors

BRCA gene variants (especially BRCA1) are closely related to the occurrence of TNBC, increasing the risk of the disease.

7. Higher mortality rate

Due to the above reasons, the mortality rate of TNBC is relatively high, and the prognosis of patients is usually poor.

How to use personalized treatment to deal with triple-negative breast cancer

1. Use comprehensive testing tools for individualized treatment

In order to provide personalized treatment, it is critical to use a comprehensive testing tool like Onconomics Plus.

2. Simple blood draw, providing accurate analysis

By simply drawing blood through liquid biopsy technology, you can obtain data on circulating tumor cells (CTCs), cancer cell gene expression, as well as chemotherapy drugs, targeted therapies and natural substances. Information on cancer cell effects.

3. CTC value

Measure the CTC values in the body. The increase or decrease in these values can show the effect of treatment, thereby guiding more effective treatment plans. Since TNBC easily metastasizes to the brain, lungs, and lymph nodes, CTC values can help in early detection of metastasis.

4. The effects of chemotherapy drugs, targeted therapies and natural substances

This test evaluates the effects of more than 50 chemotherapy drugs, more than 60 targeted drugs and more than 50 natural substances on cancer cells to determine the most effective treatment for patients options, thereby taking the guesswork out of treatment.

RGCC testing can directly test the effects of chemotherapy drugs and targeted therapies on cancer cells, providing key information for formulating the most suitable treatment plan for patients.

5. Cancer cell gene expression

This test reveals how cancer cells adapt to and resist treatment, helping to quickly develop treatment plans that provide the greatest benefit to patients before cancer cells become resistant.

If test results show that a drug is not effective in treating TNBC, doctors can quickly adjust the treatment plan to prevent the condition from rapidly worsening.

Medical Disclaimer:

The information provided in this article is for educational and informational purposes only and does not constitute medical advice and should not be used as a substitute for professional medical diagnosis, treatment or advice . Always consult your physician or other qualified health professional with any questions you may have regarding your medical condition or medical problems. The content of this article is not intended to recommend any specific test, treatment, or medication and should not be considered such advice. If you develop symptoms or require medical assistance, please contact a medical professional promptly.